Searchable abstracts of presentations at key conferences in endocrinology

ea0029p1355 | Pituitary Basic | ICEECE2012

Lycopene and β-carotene induce growth-inhibitory and proapoptotic effects on pituitary tumor cells: the mechanism could involve Connexin 43

Haddad N. , Teodoro A. , Soares N. , Oliveira F. , Mattos R. , Gomes F. , Gadelha M. , Nasciutti L. , Miranda-Alves L.

Pituitary adenomas account for ~10–15% of intracranial tumors and result in morbidity due to both altered hormonal patterns as well as side effects of therapy. Currently, great attention has been given to natural coumpouds from functional foods. Among these substances, we highlight that the consumption of carotenoids is associated with reduced risk of chronic diseases including cancer and vascular diseases. In this study we evaluate the influence of β-carotene and ly...